C1orf112 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: C1orf112
Official Name: chromosome 1 open reading frame 112
Aliases and Previous Symbols: N/A
Entrez ID: 55732
UniProt: Q9NSG2
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Olaparib 4μM R08 exp512	-2.67
Rucaparib 6.5μM R08 exp520	-2.21
Campthothecin 0.001μM R06 exp270	-2.04
Prochlorperazine 5.2μM R02 exp77	-1.94
BVD-523 15μM R02 exp67	-1.85
Talazoparib 0.006μM R06 exp299	-1.73
Nifuroxazide 5μM R03 exp102	1.72
LJH685 5μM R02 exp73	1.98

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 1672
Expression level (log2 read counts): 5.39

Expression Distribution

Last modified: 2025/12/10 20:19
by 127.0.0.1