CDH20

Entrez Summary: N/A
UniProt Summary: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Dinaciclib 0.007μM R07 exp355	-1.75
Lenalidomide 20μM R07 exp375	1.76
Benzoate 10000μM R08 exp455	1.92
ABT-702 5μM plus Dimethyloxaloylglycine 11μM R07 exp319	2.19

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Cadherin
Cadherin C

cell-cell adhesion mediated by cadherin
catenin complex
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cytoskeletal protein binding
adherens junction organization
cell-cell adherens junction
cell-cell junction assembly
cell-cell junction organization
cell junction assembly
homophilic cell adhesion via plasma membrane adhesion molecules
cell junction organization
cell-cell adhesion via plasma-membrane adhesion molecules
cadherin binding
cell-cell adhesion
cell surface
calcium ion binding
cell morphogenesis
cellular component morphogenesis
protein homodimerization activity
cell adhesion
biological adhesion