CPT1C

Entrez Summary: This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein regulates the beta-oxidation and transport of long-chain fatty acids into mitochondria, and may play a role in the regulation of feeding behavior and whole-body energy homeostasis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
UniProt Summary: May play a role in lipid metabolic process. {ECO:0000269|PubMed:25751282}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Trichostatin-A 0.06μM R07 exp415	-1.87
Benzoate 20000μM R08 exp456	1.79

carnitine O-palmitoyltransferase activity
carnitine metabolic process
amino-acid betaine metabolic process
AMPA glutamate receptor complex
regulation of postsynaptic membrane neurotransmitter receptor levels
fatty acid beta-oxidation
long-chain fatty acid transport
fatty acid transport
fatty acid oxidation
lipid oxidation
postsynapse
fatty acid catabolic process
integral component of endoplasmic reticulum membrane
monocarboxylic acid catabolic process
monocarboxylic acid transport
mitochondrial outer membrane
ammonium ion metabolic process
cellular lipid catabolic process
cellular modified amino acid metabolic process
lipid modification
carboxylic acid catabolic process
organic acid catabolic process
organic acid transport
carboxylic acid transport
axon
lipid transport
lipid catabolic process
lipid localization
fatty acid metabolic process
glutamatergic synapse
dendrite
small molecule catabolic process
organic anion transport
monocarboxylic acid metabolic process
cell junction
anion transport
carboxylic acid metabolic process
cellular lipid metabolic process
oxidation-reduction process
oxoacid metabolic process