DLX6

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Wortmannin 0.5μM R00 exp37	-2.12
Lapatinib 5μM R01 exp47	1.74

roof of mouth development
inner ear morphogenesis
ear morphogenesis
embryonic appendage morphogenesis
embryonic limb morphogenesis
appendage morphogenesis
limb morphogenesis
appendage development
limb development
positive regulation of epithelial cell proliferation
inner ear development
ear development
sensory organ morphogenesis
embryonic organ morphogenesis
regulation of epithelial cell proliferation
sequence-specific DNA binding
embryonic organ development
skeletal system development
RNA polymerase II proximal promoter sequence-specific DNA binding
sensory organ development
embryonic morphogenesis
DNA-binding transcription factor activity
epithelial cell differentiation
head development
anatomical structure formation involved in morphogenesis
positive regulation of cell population proliferation
animal organ morphogenesis
embryo development
epithelium development
positive regulation of transcription by RNA polymerase II
positive regulation of transcription, DNA-templated
DNA-binding transcription factor activity, RNA polymerase II-specific
regulation of cell population proliferation
positive regulation of nucleic acid-templated transcription
positive regulation of RNA biosynthetic process
positive regulation of RNA metabolic process
tissue development
positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process