FSD1

Entrez Summary: N/A
UniProt Summary: May be involved in microtubule organization and stabilization. {ECO:0000269|PubMed:12154070, ECO:0000269|PubMed:12445389}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
MS023 2μM R03 exp134	-1.74
THZ531 0.11 to 0.125μM on day4 R07 exp410	1.78

fn3
SPRY

regulation of mitotic spindle organization
regulation of spindle organization
cytoplasmic microtubule organization
cleavage furrow
regulation of cytokinesis
regulation of cell division
regulation of microtubule cytoskeleton organization
regulation of microtubule-based process
microtubule binding
microtubule
protein homooligomerization
supramolecular fiber organization
microtubule cytoskeleton organization
centrosome
cell division
protein complex oligomerization
regulation of cytoskeleton organization
regulation of mitotic cell cycle
microtubule-based process
regulation of cell cycle process
protein homodimerization activity
cytoskeleton organization
regulation of cell cycle
regulation of organelle organization
cell cycle
protein-containing complex assembly
protein-containing complex subunit organization