GDE1

Gene Information
  • Official Symbol: GDE1
  • Official Name: glycerophosphodiester phosphodiesterase 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 51573
  • UniProt: Q9NZC3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Has glycerophosphoinositol phosphodiesterase activity. Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity). {ECO:0000250|UniProtKB:Q9JL55, ECO:0000250|UniProtKB:Q9JL56}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 7315
  • Expression level (log2 read counts): 5.54

Expression Distribution

  • Last modified: 2025/12/10 20:19
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