GSG1L

Entrez Summary: N/A
UniProt Summary: As a component of the inner core of AMPAR complex, modifies AMPA receptor (AMPAR) gating. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

PMP22 Claudin
GSG-1

regulation of postsynaptic neurotransmitter receptor internalization
regulation of AMPA receptor activity
integral component of postsynaptic density membrane
regulation of receptor internalization
regulation of glutamate receptor signaling pathway
regulation of neurotransmitter receptor activity
Schaffer collateral - CA1 synapse
regulation of receptor-mediated endocytosis
regulation of cation channel activity
regulation of signaling receptor activity
regulation of endocytosis
regulation of ion transmembrane transporter activity
regulation of transmembrane transporter activity
regulation of transporter activity
regulation of cation transmembrane transport
glutamatergic synapse
regulation of ion transmembrane transport
regulation of cellular protein localization
cell junction
regulation of vesicle-mediated transport
regulation of transmembrane transport
regulation of ion transport
regulation of protein transport
regulation of peptide transport
regulation of establishment of protein localization
regulation of cellular localization
regulation of protein localization
regulation of transport