MTRNR2L8

Entrez Summary: N/A
UniProt Summary: Plays a role as a neuroprotective and antiapoptotic factor. {ECO:0000250|UniProtKB:Q8IVG9}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
YM155 0.001μM R08 exp432	-1.75
CCCP 0.1μM R00 exp10	1.82

negative regulation of execution phase of apoptosis
receptor antagonist activity
regulation of execution phase of apoptosis
negative regulation of signaling receptor activity
regulation of signaling receptor activity
negative regulation of apoptotic process
negative regulation of programmed cell death
negative regulation of cell death
negative regulation of molecular function
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death
extracellular region