MYO1B

Entrez Summary: N/A
UniProt Summary: Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Myosin head
Myosin TH1

actin-dependent ATPase activity
microfilament motor activity
myosin complex
cell periphery
phosphatidylinositol-3,4,5-trisphosphate binding
brush border
actin filament bundle assembly
actin filament bundle organization
apical part of cell
filopodium
phosphatidylinositol-4,5-bisphosphate binding
actin filament
trans-Golgi network membrane
post-Golgi vesicle-mediated transport
actin filament-based movement
calmodulin binding
actin filament binding
endosome membrane
actin filament organization
early endosome
cadherin binding
Golgi vesicle transport
supramolecular fiber organization
actin cytoskeleton organization
actin filament-based process
perinuclear region of cytoplasm
cytoskeleton organization
ATP binding
movement of cell or subcellular component
vesicle-mediated transport