OSBPL6

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Actinomycin-D 0.01μM R00 exp4	-2.13
UNC1999 2μM R03 exp155	1.76

sterol transporter activity
sterol binding
perinuclear endoplasmic reticulum
bile acid biosynthetic process
bile acid metabolic process
cholesterol binding
sterol transport
steroid biosynthetic process
organic hydroxy compound transport
lipid binding
monocarboxylic acid biosynthetic process
organic hydroxy compound biosynthetic process
nuclear membrane
steroid metabolic process
lipid transport
carboxylic acid biosynthetic process
organic acid biosynthetic process
lipid localization
organic hydroxy compound metabolic process
monocarboxylic acid metabolic process
lipid biosynthetic process
small molecule biosynthetic process
intracellular membrane-bounded organelle
carboxylic acid metabolic process
endoplasmic reticulum membrane
oxoacid metabolic process
organic acid metabolic process
lipid metabolic process
organic cyclic compound biosynthetic process
small molecule metabolic process
membrane