PARD6B

Gene Information
  • Official Symbol: PARD6B
  • Official Name: par-6 family cell polarity regulator beta
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 84612
  • UniProt: Q9BYG5
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 15872
  • Expression level (log2 read counts): 3.11

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1