PSPN

Entrez Summary: N/A
UniProt Summary: Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

growth factor activity
axon guidance
neuron projection guidance
signaling receptor binding
axonogenesis
MAPK cascade
signal transduction by protein phosphorylation
axon development
cell morphogenesis involved in neuron differentiation
neuron projection morphogenesis
plasma membrane bounded cell projection morphogenesis
cell projection morphogenesis
cell part morphogenesis
chemotaxis
taxis
cell morphogenesis involved in differentiation
neuron projection development
cell morphogenesis
neuron development
cellular component morphogenesis
protein phosphorylation
central nervous system development
neuron differentiation
plasma membrane bounded cell projection organization
cell projection organization
phosphorylation
locomotion
generation of neurons
movement of cell or subcellular component
extracellular space
neurogenesis
cell development
intracellular signal transduction
extracellular region