RBM17

Gene Information
  • Official Symbol: RBM17
  • Official Name: RNA binding motif protein 17
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 84991
  • UniProt: Q96I25
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. {ECO:0000269|PubMed:12015979, ECO:0000269|PubMed:17589525}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 154
  • Expression level (log2 read counts): 7.37

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1