SCARF1

Entrez Summary: N/A
UniProt Summary: Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of axon regeneration
positive regulation of neuron projection regeneration
neuron remodeling
cholesterol catabolic process
sterol catabolic process
low-density lipoprotein particle binding
regulation of axon regeneration
steroid catabolic process
regulation of neuron projection regeneration
neuron maturation
scavenger receptor activity
alcohol catabolic process
positive regulation of response to wounding
endocytic vesicle membrane
organic hydroxy compound catabolic process
dendrite development
cholesterol metabolic process
secondary alcohol metabolic process
sterol metabolic process
anatomical structure maturation
transmembrane signaling receptor activity
cell maturation
regulation of response to wounding
receptor-mediated endocytosis
developmental maturation
steroid metabolic process
positive regulation of neuron projection development
lipid catabolic process
alcohol metabolic process
positive regulation of neuron differentiation
positive regulation of cell projection organization
small molecule catabolic process
organic hydroxy compound metabolic process
positive regulation of neurogenesis
organic cyclic compound catabolic process
regulation of neuron projection development
positive regulation of nervous system development
positive regulation of cell development
endocytosis
positive regulation of response to external stimulus