SPIN3

Entrez Summary: N/A
UniProt Summary: Exhibits H3K4me3-binding activity. {ECO:0000269|PubMed:29061846}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/26
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution

Screen	Score
HMS-I1 1μM R01 exp46	1.71
LB-100 4.1μM R02 exp72	1.82

methylated histone binding
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
multi-organism reproductive process
reproductive process
reproduction