TMEM33

Gene Information
  • Official Symbol: TMEM33
  • Official Name: transmembrane protein 33
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 55161
  • UniProt: P57088
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules (PubMed:25612671). Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling (PubMed:26268696). {ECO:0000269|PubMed:25612671, ECO:0000269|PubMed:26268696}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 12702
  • Expression level (log2 read counts): 6.61

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1