UGT2B11

Entrez Summary: N/A
UniProt Summary: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Prochlorperazine 5.2μM R02 exp77	1.75
THZ531 0.225μM R08 exp444	1.84

xenobiotic glucuronidation
cellular glucuronidation
UDP-glycosyltransferase activity
uronic acid metabolic process
glucuronate metabolic process
glucuronosyltransferase activity
estrogen metabolic process
cellular hormone metabolic process
xenobiotic metabolic process
cellular response to xenobiotic stimulus
monosaccharide metabolic process
hormone metabolic process
steroid metabolic process
response to xenobiotic stimulus
carbohydrate metabolic process
monocarboxylic acid metabolic process
regulation of hormone levels
intracellular membrane-bounded organelle
carboxylic acid metabolic process
endoplasmic reticulum membrane
oxoacid metabolic process
organic acid metabolic process
lipid metabolic process
small molecule metabolic process