AAGAB

Gene Information
  • Official Symbol: AAGAB
  • Official Name: alpha and gamma adaptin binding protein
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 79719
  • UniProt: Q6PD74
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012].
  • UniProt Summary: May be involved in endocytic recycling of growth factor receptors such as EGFR. {ECO:0000269|PubMed:23064416}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 2437
  • Expression level (log2 read counts): 5.83

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1