AMTN

Entrez Summary: N/A
UniProt Summary: Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. {ECO:0000269|PubMed:25407797}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of enamel mineralization
positive regulation of odontogenesis of dentin-containing tooth
regulation of enamel mineralization
positive regulation of tooth mineralization
regulation of tooth mineralization
positive regulation of odontogenesis
regulation of odontogenesis of dentin-containing tooth
regulation of odontogenesis
positive regulation of biomineral tissue development
positive regulation of biomineralization
positive regulation of animal organ morphogenesis
odontogenesis of dentin-containing tooth
basement membrane
regulation of biomineralization
biomineralization
regulation of biomineral tissue development
biomineral tissue development
odontogenesis
cell-cell junction
extracellular matrix
regulation of animal organ morphogenesis
endoplasmic reticulum lumen
post-translational protein modification
molecular function
cell adhesion
biological adhesion
animal organ morphogenesis
regulation of anatomical structure morphogenesis
positive regulation of developmental process
positive regulation of multicellular organismal process
tissue development