APOLD1

Entrez Summary: N/A
UniProt Summary: May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood- brain permeability. {ECO:0000269|PubMed:15102925}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
SNS-032 25μM R07 exp401	-2.04
Docetaxel 0.001 to 0.002μM on day4 R04 exp159	1.75

endothelial cell activation
regulation of endothelial cell differentiation
lipoprotein metabolic process
regulation of epithelial cell differentiation
lipid binding
lipid transport
angiogenesis
lipid localization
response to hypoxia
response to decreased oxygen levels
response to oxygen levels
blood vessel morphogenesis
blood vessel development
vasculature development
cardiovascular system development
tube morphogenesis
tube development
circulatory system development
anatomical structure formation involved in morphogenesis
cell activation
response to abiotic stimulus
regulation of cell differentiation
extracellular region