ARHGAP17

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

RhoGAP
BAR

calcium-ion regulated exocytosis
Rac GTPase binding
bicellular tight junction
SH3 domain binding
actin filament organization
GTPase activator activity
regulation of actin cytoskeleton organization
regulation of small GTPase mediated signal transduction
regulation of actin filament-based process
positive regulation of GTPase activity
supramolecular fiber organization
regulation of GTPase activity
actin cytoskeleton organization
regulation of cytoskeleton organization
actin filament-based process
regulated exocytosis
positive regulation of hydrolase activity
exocytosis
secretion by cell
export from cell
cytoskeleton organization
secretion
regulation of hydrolase activity
regulation of organelle organization
positive regulation of catalytic activity
positive regulation of molecular function
regulation of intracellular signal transduction
vesicle-mediated transport