ARSA

Gene Information
  • Official Symbol: ARSA
  • Official Name: arylsulfatase A
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 410
  • UniProt: P15289
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010].
  • UniProt Summary: Hydrolyzes cerebroside sulfate.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 4695
  • Expression level (log2 read counts): 3.37

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1