ASAH2B

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Ibrutinib 10μM R08 exp442	-1.74
FBS-Wisent 0.1 R07 exp426	1.97

N-acylsphingosine amidohydrolase activity
sphingosine biosynthetic process
sphingoid biosynthetic process
sphingosine metabolic process
sphingoid metabolic process
diol biosynthetic process
ceramide catabolic process
diol metabolic process
long-chain fatty acid biosynthetic process
sphingolipid catabolic process
membrane lipid catabolic process
polyol biosynthetic process
ceramide metabolic process
sphingolipid biosynthetic process
polyol metabolic process
alcohol biosynthetic process
long-chain fatty acid metabolic process
fatty acid biosynthetic process
membrane lipid biosynthetic process
sphingolipid metabolic process
monocarboxylic acid biosynthetic process
organic hydroxy compound biosynthetic process
ammonium ion metabolic process
cellular lipid catabolic process
membrane lipid metabolic process
lipid catabolic process
carboxylic acid biosynthetic process
organic acid biosynthetic process
alcohol metabolic process
fatty acid metabolic process
organic hydroxy compound metabolic process
monocarboxylic acid metabolic process
lipid biosynthetic process
small molecule biosynthetic process
cellular amide metabolic process
carboxylic acid metabolic process
cellular lipid metabolic process
oxoacid metabolic process
organic acid metabolic process
organonitrogen compound catabolic process