ASGR1

Gene Information
  • Official Symbol: ASGR1
  • Official Name: asialoglycoprotein receptor 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 432
  • UniProt: P07306
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 14315
  • Expression level (log2 read counts): 2.33

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1