BET1

Entrez Summary: N/A
UniProt Summary: Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 2/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	1/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

vesicle fusion with Golgi apparatus
Golgi trans cisterna
SNAP receptor activity
SNARE complex
COPII vesicle coating
vesicle targeting, rough ER to cis-Golgi
integral component of Golgi membrane
vesicle coating
COPII-coated vesicle budding
endoplasmic reticulum-Golgi intermediate compartment membrane
vesicle targeting, to, from or within Golgi
vesicle fusion
Golgi vesicle budding
organelle membrane fusion
vesicle targeting
transport vesicle
organelle fusion
vesicle budding from membrane
membrane fusion
establishment of vesicle localization
vesicle localization
endoplasmic reticulum to Golgi vesicle-mediated transport
vesicle organization
establishment of organelle localization
Golgi vesicle transport
organelle localization
Golgi membrane
membrane organization
endoplasmic reticulum membrane
protein transport
intracellular transport
peptide transport
protein-containing complex assembly
amide transport
establishment of protein localization
establishment of localization in cell
nitrogen compound transport
protein-containing complex subunit organization
vesicle-mediated transport
membrane