BRINP1

Entrez Summary: N/A
UniProt Summary: Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway. {ECO:0000269|PubMed:11420708, ECO:0000269|PubMed:14712213, ECO:0000269|PubMed:16369496}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

short-term memory
maternal behavior
parental behavior
vocalization behavior
exploration behavior
reproductive behavior
behavioral fear response
behavioral defense response
fear response
social behavior
intraspecies interaction between organisms
multi-organism behavior
multicellular organismal response to stress
cellular response to retinoic acid
response to retinoic acid
memory
cell cycle arrest
cellular response to acid chemical
learning or memory
negative regulation of neurogenesis
cognition
negative regulation of mitotic cell cycle
negative regulation of nervous system development
negative regulation of cell development
response to acid chemical
positive regulation of neuron differentiation
neuronal cell body
dendrite
positive regulation of neurogenesis
cellular response to lipid
positive regulation of nervous system development
positive regulation of cell development
behavior
negative regulation of cell cycle
regulation of mitotic cell cycle
regulation of neuron differentiation
negative regulation of cell differentiation
regulation of neurogenesis
multicellular organismal reproductive process
multicellular organism reproduction