C2CD4B

Entrez Summary: N/A
UniProt Summary: May be involved in inflammatory process. May regulate cell architecture and adhesion. {ECO:0000269|PubMed:15527968}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Hypoxia 5%O2 R04 exp191	-2.25
Etoposide 0.1μM R05 exp198	1.71

regulation of vascular permeability involved in acute inflammatory response
positive regulation of acute inflammatory response
regulation of vascular permeability
regulation of acute inflammatory response
acute inflammatory response
positive regulation of inflammatory response
vascular process in circulatory system
regulation of inflammatory response
blood circulation
circulatory system process
positive regulation of defense response
inflammatory response
positive regulation of response to external stimulus
regulation of cell adhesion
regulation of defense response
regulation of response to external stimulus
defense response
regulation of response to stress
system process