C6orf165

Entrez Summary: N/A
UniProt Summary: May regulate cilium motility through its role in the assembly of the axonemal radial spokes. {ECO:0000250|UniProtKB:Q23H79}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Deferoxamine 11μM R07 exp350	-1.7
JQ1 0.8μM R08 exp435	1.73

A axonemal microtubule
radial spoke
cilium movement
axoneme assembly
microtubule bundle formation
motile cilium
microtubule-based movement
cilium assembly
cilium organization
plasma membrane bounded cell projection assembly
cell projection assembly
microtubule cytoskeleton organization
microtubule-based process
organelle assembly
cytoskeleton organization
plasma membrane bounded cell projection organization
cell projection organization
movement of cell or subcellular component