CARHSP1

Entrez Summary: N/A
UniProt Summary: Binds mRNA and regulates the stability of target mRNA. Binds single-stranded DNA (in vitro). {ECO:0000269|PubMed:21078874, ECO:0000269|PubMed:21177848}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Epigallocatechin gallate 20μM R05 exp230	1.77
RK-33 8μM R08 exp518	1.77

cytoplasmic exosome (RNase complex)
P granule
phosphatase binding
mRNA 3-UTR binding
P-body
regulation of mRNA stability
regulation of RNA stability
regulation of mRNA catabolic process
regulation of mRNA metabolic process
posttranscriptional regulation of gene expression
regulation of cellular catabolic process
regulation of catabolic process
DNA-binding transcription factor activity, RNA polymerase II-specific
intracellular signal transduction