CCDC64

Entrez Summary: N/A
UniProt Summary: Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Golgi to secretory granule transport
dynactin binding
vesicle transport along microtubule
vesicle cytoskeletal trafficking
organelle transport along microtubule
Rab GTPase binding
transport along microtubule
establishment of vesicle localization
cytoskeleton-dependent intracellular transport
microtubule-based transport
vesicle localization
microtubule-based movement
establishment of organelle localization
centrosome
organelle localization
neuron projection development
microtubule-based process
neuron development
neuron differentiation
plasma membrane bounded cell projection organization
cell projection organization
intracellular transport
generation of neurons
movement of cell or subcellular component
neurogenesis
cell development
establishment of localization in cell