CLEC3B

Entrez Summary: N/A
UniProt Summary: Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Pyronaridine 1μM R06 exp295	1.75
S-DABN 8μM R03 exp112	1.77

kringle domain binding
granular component
positive regulation of plasminogen activation
regulation of plasminogen activation
platelet dense granule lumen
positive regulation of protein processing
positive regulation of protein maturation
bone mineralization
regulation of protein processing
regulation of protein maturation
biomineralization
biomineral tissue development
platelet degranulation
cellular response to transforming growth factor beta stimulus
response to transforming growth factor beta
heparin binding
carbohydrate binding
ossification
positive regulation of proteolysis
collagen-containing extracellular matrix
cellular response to growth factor stimulus
response to growth factor
regulated exocytosis
calcium ion binding
regulation of proteolysis
exocytosis
secretion by cell
export from cell
secretion
cellular response to endogenous stimulus
response to endogenous stimulus
extracellular space
positive regulation of cellular protein metabolic process
positive regulation of protein metabolic process
tissue development
extracellular region
vesicle-mediated transport
positive regulation of gene expression