COLEC11
Gene Information
- Official Symbol: COLEC11
- Official Name: collectin subfamily member 11
- Aliases and Previous Symbols: N/A
- Entrez ID: 78989
- UniProt: Q9BWP8
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 6597
- Expression level (log2 read counts): -0.82
COLEC11 Expression in NALM6 Cells: -0.82
