CPT2

Entrez Summary: The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders. [provided by RefSeq, Jul 2008].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

carnitine O-palmitoyltransferase activity
carnitine shuttle
fatty acid transmembrane transport
intracellular lipid transport
fatty acid beta-oxidation
long-chain fatty acid transport
fatty acid transport
fatty acid oxidation
lipid oxidation
mitochondrial transmembrane transport
fatty acid catabolic process
positive regulation of cold-induced thermogenesis
monocarboxylic acid catabolic process
organic acid transmembrane transport
carboxylic acid transmembrane transport
monocarboxylic acid transport
regulation of cold-induced thermogenesis
cellular lipid catabolic process
lipid modification
mitochondrial transport
organic acid catabolic process
carboxylic acid catabolic process
anion transmembrane transport
organic acid transport
carboxylic acid transport
lipid transport
lipid catabolic process
lipid localization
fatty acid metabolic process
in utero embryonic development
regulation of lipid metabolic process
mitochondrial inner membrane
small molecule catabolic process
organic anion transport
monocarboxylic acid metabolic process
anion transport
chordate embryonic development
embryo development ending in birth or egg hatching
nucleolus
carboxylic acid metabolic process