CSN2

Entrez Summary: N/A
UniProt Summary: Important role in determination of the surface properties of the casein micelles.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of lactation
regulation of lactation
enzyme inhibitor activity
cysteine-type endopeptidase inhibitor activity
lactation
body fluid secretion
negative regulation of cysteine-type endopeptidase activity
mammary gland development
negative regulation of secretion
regulation of cysteine-type endopeptidase activity
negative regulation of endopeptidase activity
calcium ion transport
negative regulation of peptidase activity
divalent metal ion transport
divalent inorganic cation transport
negative regulation of proteolysis
gland development
regulation of endopeptidase activity
regulation of peptidase activity
negative regulation of hydrolase activity
negative regulation of transport
regulation of body fluid levels
metal ion transport
calcium ion binding
regulation of proteolysis
negative regulation of catalytic activity
regulation of secretion
cation transport
negative regulation of developmental process
negative regulation of cellular protein metabolic process
negative regulation of protein metabolic process
secretion
negative regulation of molecular function
negative regulation of multicellular organismal process
regulation of hydrolase activity
ion transport
extracellular space
regulation of transport
extracellular region