CSNK1G3

Entrez Summary: N/A
UniProt Summary: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

peptidyl-threonine phosphorylation
peptidyl-threonine modification
positive regulation of canonical Wnt signaling pathway
peptidyl-serine phosphorylation
positive regulation of Wnt signaling pathway
peptidyl-serine modification
protein kinase activity
regulation of canonical Wnt signaling pathway
cell-cell signaling by wnt
Wnt signaling pathway
regulation of Wnt signaling pathway
protein serine/threonine kinase activity
cell surface receptor signaling pathway involved in cell-cell signaling
endocytosis
import into cell
peptidyl-amino acid modification
protein phosphorylation
cell-cell signaling
phosphorylation
ATP binding
positive regulation of signal transduction
positive regulation of cell communication
positive regulation of signaling
vesicle-mediated transport