CUEDC2

Gene Information
  • Official Symbol: CUEDC2
  • Official Name: CUE domain containing 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 79004
  • UniProt: Q9H467
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. {ECO:0000269|PubMed:17347654, ECO:0000269|PubMed:21572428}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 5079
  • Expression level (log2 read counts): 5.15

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1