DARS2 [The Human Chemical-Genetic Interaction Map Project]

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======= DARS2 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: DARS2
  * **<color #00a2e8>Official Name</color>**: aspartyl-tRNA synthetase 2, mitochondrial
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=55157|55157]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q6PI48|Q6PI48]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=DARS2&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20DARS2|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/610956|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**:  The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). [provided by RefSeq, Nov 2009]. 
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|GAD|
|tRNA anti|
|tRNA-synt 2|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|mitochondrial asparaginyl-tRNA aminoacylation|
|aspartate-tRNA(Asn) ligase activity|
|aspartate-tRNA ligase activity|
|asparaginyl-tRNA aminoacylation|
|tRNA aminoacylation for mitochondrial protein translation|
|mitochondrial RNA metabolic process|
|tRNA aminoacylation for protein translation|
|tRNA aminoacylation|
|amino acid activation|
|tRNA binding|
|mitochondrial translation|
|mitochondrial gene expression|
|tRNA metabolic process|
|cellular amino acid metabolic process|
|mitochondrial matrix|
|translation|
|peptide biosynthetic process|
|ncRNA metabolic process|
|amide biosynthetic process|
|peptide metabolic process|
|cellular amide metabolic process|
|protein homodimerization activity|
|carboxylic acid metabolic process|
|oxoacid metabolic process|
|organic acid metabolic process|
|mitochondrion|
|organonitrogen compound biosynthetic process|
|ATP binding|
|cellular nitrogen compound biosynthetic process|
|RNA metabolic process|
|cellular macromolecule biosynthetic process|
|small molecule metabolic process|
|macromolecule biosynthetic process|
|gene expression|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp430|Rifampicin 30μM R08 exp430]]|-2.9|
|[[:results:exp482|Fas-L 44ng/ml R08 exp482]]|-2.75|
|[[:results:exp260|ABT-702 0.1μM R06 exp260]]|-2.53|
|[[:results:exp159|Docetaxel 0.001 to 0.002μM on day4 R04 exp159]]|-2.22|
|[[:results:exp480|ETC-159 50μM R08 exp480]]|-2.22|
|[[:results:exp495|IWR1 50μM R08 exp495]]|-2.13|
|[[:results:exp287|HMS-I2 5μM R06 exp287]]|-2.1|
|[[:results:exp215|Colchicine 0.009μM R05 exp215]]|-2.08|
|[[:results:exp461|BS-181 20μM R08 exp461]]|-2.05|
|[[:results:exp278|CVT-10216 0.1μM R06 exp278]]|-2.02|
|[[:results:exp40|2-Methoxyestradiol 0.2μM R01 exp40]]|-1.84|
|[[:results:exp519|RS-1 10μM R08 exp519]]|-1.79|
|[[:results:exp41|BI-2536 0.001μM R01 exp41]]|-1.77|
|[[:results:exp1|5-Fluorouracil 2μM R00 exp1]]|-1.74|
|[[:results:exp261|ABT-702 5μM R06 exp261]]|-1.74|
|[[:results:exp133|MKC9989 10μM R03 exp133]]|-1.72|
|[[:results:exp453|B02 10μM R08 exp453]]|-1.7|
|[[:results:exp66|BI-D1870 3.15μM R02 exp66]]|1.7|
|[[:results:exp469|CFI-400945 25μM R08 exp469]]|1.7|
|[[:results:exp488|Hippuristanol 0.12μM R08 exp488]]|1.78|
|[[:results:exp106|UM131593 0.2μM R03 exp106]]|1.79|
|[[:results:exp89|Vemurafenib 6.6μM R02 exp89]]|1.8|
|[[:results:exp525|Sulforaphane 9μM R08 exp525]]|1.8|
|[[:results:exp111|R-DABN 8μM R03 exp111]]|1.81|
|[[:results:exp85|UM0129480 7μM R02 exp85]]|1.83|
|[[:results:exp93|DABN racemic mixture R03 exp93]]|1.85|
|[[:results:exp25|Oligomycin-A 2μM R00 exp25]]|2.1|
|[[:results:exp504|MK2206 4μM R08 exp504]]|2.17|
|[[:results:exp71|KU-0063794 3.8μM R02 exp71]]|2.18|
|[[:results:exp342|Calcium Ionophore 0.4μM R07 exp342]]|2.19|
|[[:results:exp78|Pterostilbene 16μM R02 exp78]]|2.25|
|[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|2.26|
|[[:results:exp290|LLY-283 2.6μM R06 exp290]]|2.31|
|[[:results:exp532|TIC10 10μM R08 exp532]]|2.42|
|[[:results:exp439|QNZ 0.01μM R08 exp439]]|2.44|
|[[:results:exp65|Mubritinib 0.2μM R02 exp65]]|2.46|
|[[:results:exp521|Salinomycin 3.5μM R08 exp521]]|2.46|
|[[:results:exp527|Tanespimycin 14μM R08 exp527]]|2.52|
|[[:results:exp329|Hydroxyurea 100μM R07 exp329]]|2.63|
|[[:results:exp84|UM0125461 0.74μM R02 exp84]]|2.72|
|[[:results:exp116|AICAR 240μM R03 exp116]]|2.75|
|[[:results:exp515|PU-H71 1μM R08 exp515]]|2.95|
|[[:results:exp529|Thimerosal 0.85μM R08 exp529]]|3.18|
|[[:results:exp441|GSK-J4 1.5μM R08 exp441]]|3.2|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:h:hsd17b10|HSD17B10]]|0.783|
|[[:human genes:m:mrps14|MRPS14]]|0.726|
|[[:human genes:g:gfm1|GFM1]]|0.714|
|[[:human genes:b:bcs1l|BCS1L]]|0.712|
|[[:human genes:m:mrpl21|MRPL21]]|0.695|
|[[:human genes:d:dap3|DAP3]]|0.694|
|[[:human genes:m:mrp63|MRP63]]|0.688|
|[[:human genes:n:nars2|NARS2]]|0.685|
|[[:human genes:m:mrps26|MRPS26]]|0.684|
|[[:human genes:m:mrps16|MRPS16]]|0.682|
|[[:human genes:y:yars2|YARS2]]|0.679|
|[[:human genes:s:sco2|SCO2]]|0.668|
|[[:human genes:c:cox16|COX16]]|0.667|
|[[:human genes:q:qrsl1|QRSL1]]|0.666|
|[[:human genes:v:vars2|VARS2]]|0.661|
|[[:human genes:m:mrps5|MRPS5]]|0.659|
|[[:human genes:m:mrps34|MRPS34]]|0.658|
|[[:human genes:t:tars2|TARS2]]|0.652|
|[[:human genes:m:mrps6|MRPS6]]|0.643|
|[[:human genes:r:rars2|RARS2]]|0.641|
|[[:human genes:c:coa3|COA3]]|0.641|
|[[:human genes:p:pars2|PARS2]]|0.639|
|[[:human genes:m:mrps21|MRPS21]]|0.638|
|[[:human genes:r:rpusd4|RPUSD4]]|0.633|
|[[:human genes:l:lars2|LARS2]]|0.633|
|[[:human genes:s:selrc1|SELRC1]]|0.632|
|[[:human genes:c:c10orf2|C10orf2]]|0.63|
|[[:human genes:m:mrpl23|MRPL23]]|0.63|
|[[:human genes:f:fars2|FARS2]]|0.629|
|[[:human genes:g:gfm2|GFM2]]|0.626|
|[[:human genes:m:mrpl47|MRPL47]]|0.622|
|[[:human genes:m:mrpl53|MRPL53]]|0.621|
|[[:human genes:s:supv3l1|SUPV3L1]]|0.621|
|[[:human genes:m:mars2|MARS2]]|0.619|
|[[:human genes:e:ears2|EARS2]]|0.615|
|[[:human genes:t:tefm|TEFM]]|0.614|
|[[:human genes:m:mrps2|MRPS2]]|0.609|
|[[:human genes:k:kiaa0391|KIAA0391]]|0.608|
|[[:human genes:w:wbscr16|WBSCR16]]|0.605|
|[[:human genes:s:slc25a26|SLC25A26]]|0.598|
|[[:human genes:t:tufm|TUFM]]|0.598|
|[[:human genes:s:sars2|SARS2]]|0.594|
|[[:human genes:h:hars2|HARS2]]|0.592|
|[[:human genes:m:mrps18a|MRPS18A]]|0.589|
|[[:human genes:n:ndufa3|NDUFA3]]|0.586|
|[[:human genes:m:mrps33|MRPS33]]|0.583|
|[[:human genes:n:ndufb11|NDUFB11]]|0.582|
|[[:human genes:f:ftsj2|FTSJ2]]|0.582|
|[[:human genes:c:cox7b|COX7B]]|0.581|
|[[:human genes:m:mrps9|MRPS9]]|0.579|
|[[:human genes:m:mrpl45|MRPL45]]|0.577|
|[[:human genes:n:ndufaf7|NDUFAF7]]|0.574|
|[[:human genes:c:cox17|COX17]]|0.572|
|[[:human genes:u:uqcrc2|UQCRC2]]|0.571|
|[[:human genes:r:rbfa|RBFA]]|0.571|
|[[:human genes:m:mrps25|MRPS25]]|0.57|
|[[:human genes:p:pnpt1|PNPT1]]|0.57|
|[[:human genes:g:gtpbp10|GTPBP10]]|0.57|
|[[:human genes:n:ndufa1|NDUFA1]]|0.57|
|[[:human genes:a:aars2|AARS2]]|0.569|
|[[:human genes:f:fastkd5|FASTKD5]]|0.567|
|[[:human genes:m:mrpl20|MRPL20]]|0.566|
|[[:human genes:m:mrps12|MRPS12]]|0.565|
|[[:human genes:a:atp5d|ATP5D]]|0.56|
|[[:human genes:c:c12orf65|C12orf65]]|0.558|
|[[:human genes:r:rpusd3|RPUSD3]]|0.557|
|[[:human genes:g:gatc|GATC]]|0.554|
|[[:human genes:a:aifm1|AIFM1]]|0.553|
|[[:human genes:m:mrpl15|MRPL15]]|0.551|
|[[:human genes:m:mrpl3|MRPL3]]|0.551|
|[[:human genes:c:cars2|CARS2]]|0.55|
|[[:human genes:t:trub2|TRUB2]]|0.55|
|[[:human genes:p:pgm3|PGM3]]|0.546|
|[[:human genes:m:mrps24|MRPS24]]|0.544|
|[[:human genes:p:pet117|PET117]]|0.543|
|[[:human genes:p:pet112|PET112]]|0.542|
|[[:human genes:p:polrmt|POLRMT]]|0.542|
|[[:human genes:f:fh|FH]]|0.541|
|[[:human genes:r:rnaseh1|RNASEH1]]|0.54|
|[[:human genes:m:mrpl42|MRPL42]]|0.534|
|[[:human genes:a:atp5b|ATP5B]]|0.529|
|[[:human genes:p:polg|POLG]]|0.527|
|[[:human genes:m:mrps23|MRPS23]]|0.526|
|[[:human genes:e:elac2|ELAC2]]|0.526|
|[[:human genes:a:atp5j|ATP5J]]|0.525|
|[[:human genes:m:mtrf1l|MTRF1L]]|0.524|
|[[:human genes:r:rtn4ip1|RTN4IP1]]|0.523|
|[[:human genes:c:cox11|COX11]]|0.522|
|[[:human genes:n:ndufc2|NDUFC2]]|0.522|
|[[:human genes:c:cox15|COX15]]|0.521|
|[[:human genes:d:dhrsx|DHRSX]]|0.519|
|[[:human genes:m:mrpl39|MRPL39]]|0.519|
|[[:human genes:m:mrpl33|MRPL33]]|0.515|
|[[:human genes:m:mrpl18|MRPL18]]|0.514|
|[[:human genes:l:lsm10|LSM10]]|0.514|
|[[:human genes:a:atp5a1|ATP5A1]]|0.514|
|[[:human genes:d:dnlz|DNLZ]]|0.514|
|[[:human genes:m:mrps11|MRPS11]]|0.512|
|[[:human genes:m:mrpl43|MRPL43]]|0.51|
|[[:human genes:t:tfam|TFAM]]|0.509|
|[[:human genes:a:atp5c1|ATP5C1]]|0.508|
|[[:human genes:p:pdss1|PDSS1]]|0.506|
|[[:human genes:m:mrpl12|MRPL12]]|0.505|
|[[:human genes:n:ndufaf4|NDUFAF4]]|0.504|
|[[:human genes:m:mrpl44|MRPL44]]|0.504|
|[[:human genes:m:mtpap|MTPAP]]|0.503|
|[[:human genes:m:mrpl17|MRPL17]]|0.502|
|[[:human genes:c:coa6|COA6]]|0.497|
|[[:human genes:a:atp5sl|ATP5SL]]|0.495|
|[[:human genes:m:mtg2|MTG2]]|0.493|
|[[:human genes:n:ndufb6|NDUFB6]]|0.493|
|[[:human genes:a:aasdhppt|AASDHPPT]]|0.493|
|[[:human genes:t:triap1|TRIAP1]]|0.493|
|[[:human genes:n:ndufv1|NDUFV1]]|0.493|
|[[:human genes:n:nfu1|NFU1]]|0.492|
|[[:human genes:m:mrpl55|MRPL55]]|0.492|
|[[:human genes:h:hccs|HCCS]]|0.491|
|[[:human genes:v:vezt|VEZT]]|0.49|
|[[:human genes:t:tomm20|TOMM20]]|0.489|
|[[:human genes:n:ndufb5|NDUFB5]]|0.489|
|[[:human genes:c:cox6c|COX6C]]|0.489|
|[[:human genes:a:atic|ATIC]]|0.486|
|[[:human genes:n:ndufa2|NDUFA2]]|0.485|
|[[:human genes:c:chchd4|CHCHD4]]|0.485|
|[[:human genes:c:coa5|COA5]]|0.484|
|[[:human genes:m:mrpl11|MRPL11]]|0.483|
|[[:human genes:n:ndufaf3|NDUFAF3]]|0.481|
|[[:human genes:m:mrpl52|MRPL52]]|0.481|
|[[:human genes:u:uqcr10|UQCR10]]|0.48|
|[[:human genes:p:polg2|POLG2]]|0.48|
|[[:human genes:m:mrps7|MRPS7]]|0.479|
|[[:human genes:t:tfb1m|TFB1M]]|0.479|
|[[:human genes:m:mettl17|METTL17]]|0.479|
|[[:human genes:m:mterfd1|MTERFD1]]|0.478|
|[[:human genes:c:cox5a|COX5A]]|0.477|
|[[:human genes:t:thg1l|THG1L]]|0.477|
|[[:human genes:a:atp5o|ATP5O]]|0.476|
|[[:human genes:a:atxn10|ATXN10]]|0.475|
|[[:human genes:d:dolk|DOLK]]|0.475|
|[[:human genes:w:wars2|WARS2]]|0.475|
|[[:human genes:r:rpia|RPIA]]|0.473|
|[[:human genes:m:mrpl36|MRPL36]]|0.473|
|[[:human genes:c:c17orf89|C17orf89]]|0.473|
|[[:human genes:m:mrps22|MRPS22]]|0.473|
|[[:human genes:t:trmt61a|TRMT61A]]|0.472|
|[[:human genes:d:dpagt1|DPAGT1]]|0.472|
|[[:human genes:p:ppcs|PPCS]]|0.472|
|[[:human genes:g:gtpbp8|GTPBP8]]|0.471|
|[[:human genes:t:tmem242|TMEM242]]|0.468|
|[[:human genes:m:mrpl4|MRPL4]]|0.468|
|[[:human genes:m:mrpl22|MRPL22]]|0.466|
|[[:human genes:m:malsu1|MALSU1]]|0.465|
|[[:human genes:m:mrpl32|MRPL32]]|0.464|
|[[:human genes:s:ssb|SSB]]|0.464|
|[[:human genes:m:mrpl34|MRPL34]]|0.462|
|[[:human genes:s:sdha|SDHA]]|0.462|
|[[:human genes:c:cox6b1|COX6B1]]|0.46|
|[[:human genes:m:mterfd2|MTERFD2]]|0.459|
|[[:human genes:p:ppa2|PPA2]]|0.459|
|[[:human genes:a:alg6|ALG6]]|0.457|
|[[:human genes:t:trmt10c|TRMT10C]]|0.456|
|[[:human genes:m:mrps10|MRPS10]]|0.456|
|[[:human genes:n:ndufs2|NDUFS2]]|0.455|
|[[:human genes:a:atp5h|ATP5H]]|0.455|
|[[:human genes:n:ndufb9|NDUFB9]]|0.455|
|[[:human genes:s:srd5a3|SRD5A3]]|0.449|
|[[:human genes:m:mrps27|MRPS27]]|0.447|
|[[:human genes:m:mrpl41|MRPL41]]|0.446|
|[[:human genes:r:rnmtl1|RNMTL1]]|0.445|
|[[:human genes:s:slc25a19|SLC25A19]]|0.445|
|[[:human genes:p:pmm2|PMM2]]|0.444|
|[[:human genes:n:ndufb3|NDUFB3]]|0.444|
|[[:human genes:d:ddx28|DDX28]]|0.442|
|[[:human genes:t:tomm22|TOMM22]]|0.441|
|[[:human genes:r:rft1|RFT1]]|0.441|
|[[:human genes:t:timmdc1|TIMMDC1]]|0.439|
|[[:human genes:k:kdsr|KDSR]]|0.439|
|[[:human genes:c:cox19|COX19]]|0.438|
|[[:human genes:a:atp5l|ATP5L]]|0.437|
|[[:human genes:n:ndufb1|NDUFB1]]|0.436|
|[[:human genes:a:alg1|ALG1]]|0.435|
|[[:human genes:c:crls1|CRLS1]]|0.435|
|[[:human genes:c:coq4|COQ4]]|0.434|
|[[:human genes:m:mrps17|MRPS17]]|0.434|
|[[:human genes:m:mrpl27|MRPL27]]|0.433|
|[[:human genes:u:uqcrq|UQCRQ]]|0.43|
|[[:human genes:a:atp5f1|ATP5F1]]|0.43|
|[[:human genes:i:iba57|IBA57]]|0.43|
|[[:human genes:h:higd2a|HIGD2A]]|0.429|
|[[:human genes:s:slc25a52|SLC25A52]]|0.429|
|[[:human genes:o:opa1|OPA1]]|0.429|
|[[:human genes:d:dhx30|DHX30]]|0.428|
|[[:human genes:d:dohh|DOHH]]|0.428|
|[[:human genes:s:slc25a3|SLC25A3]]|0.428|
|[[:human genes:m:mtif3|MTIF3]]|0.428|
|[[:human genes:c:cycs|CYCS]]|0.428|
|[[:human genes:r:romo1|ROMO1]]|0.427|
|[[:human genes:t:tamm41|TAMM41]]|0.426|
|[[:human genes:m:mrpl28|MRPL28]]|0.426|
|[[:human genes:n:ndufs7|NDUFS7]]|0.425|
|[[:human genes:t:trnt1|TRNT1]]|0.425|
|[[:human genes:t:taz|TAZ]]|0.425|
|[[:human genes:m:mrpl35|MRPL35]]|0.424|
|[[:human genes:p:pet100|PET100]]|0.424|
|[[:human genes:t:tpk1|TPK1]]|0.424|
|[[:human genes:s:sco1|SCO1]]|0.423|
|[[:human genes:m:mipep|MIPEP]]|0.421|
|[[:human genes:t:trmt10a|TRMT10A]]|0.421|
|[[:human genes:c:chchd1|CHCHD1]]|0.42|
|[[:human genes:c:cox20|COX20]]|0.42|
|[[:human genes:h:hmgxb3|HMGXB3]]|0.418|
|[[:human genes:n:ndufaf5|NDUFAF5]]|0.418|
|[[:human genes:m:mtg1|MTG1]]|0.418|
|[[:human genes:t:tomm40|TOMM40]]|0.418|
|[[:human genes:c:clpp|CLPP]]|0.417|
|[[:human genes:a:alg8|ALG8]]|0.416|
|[[:human genes:e:ecsit|ECSIT]]|0.416|
|[[:human genes:n:ndufa11|NDUFA11]]|0.416|
|[[:human genes:n:ndufs5|NDUFS5]]|0.416|
|[[:human genes:c:coq6|COQ6]]|0.414|
|[[:human genes:z:zrsr2|ZRSR2]]|0.413|
|[[:human genes:a:aldh18a1|ALDH18A1]]|0.411|
|[[:human genes:m:mrps18b|MRPS18B]]|0.41|
|[[:human genes:a:acad9|ACAD9]]|0.409|
|[[:human genes:r:rfk|RFK]]|0.409|
|[[:human genes:s:ssbp1|SSBP1]]|0.409|
|[[:human genes:p:ptcd3|PTCD3]]|0.409|
|[[:human genes:z:zcrb1|ZCRB1]]|0.408|
|[[:human genes:m:mrps35|MRPS35]]|0.407|
|[[:human genes:m:mrpl49|MRPL49]]|0.406|
|[[:human genes:e:eny2|ENY2]]|0.405|
|[[:human genes:t:timm8b|TIMM8B]]|0.405|
|[[:human genes:m:mrpl13|MRPL13]]|0.405|
|[[:human genes:c:coq2|COQ2]]|0.404|
|[[:human genes:u:uap1|UAP1]]|0.404|
|[[:human genes:m:mrpl37|MRPL37]]|0.404|
|[[:human genes:g:grsf1|GRSF1]]|0.404|
|[[:human genes:a:atp5e|ATP5E]]|0.403|
|[[:human genes:m:mrpl9|MRPL9]]|0.402|
|[[:human genes:u:uhrf1|UHRF1]]|0.401|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 8/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|1/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|1/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|1/21|
|liver|0/20|
|lung|1/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 42
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.98 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='DARS2 Expression in NALM6 Cells: 5.98'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>