DOK2

Gene Information
  • Official Symbol: DOK2
  • Official Name: docking protein 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 9046
  • UniProt: O60496
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity). {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 2809
  • Expression level (log2 read counts): -3.28

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1