DUPD1

Official Symbol: DUPD1
Official Name: dual specificity phosphatase and pro isomerase domain containing 1
Aliases and Previous Symbols: N/A
Entrez ID: 338599
UniProt: Q68J44
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Entrez Summary: N/A
UniProt Summary: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. {ECO:0000269|PubMed:17498703}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

protein tyrosine/serine/threonine phosphatase activity
protein tyrosine phosphatase activity
peptidyl-tyrosine dephosphorylation
protein dephosphorylation
dephosphorylation
protein-containing complex
protein homodimerization activity