ECE1

• Official Symbol: ECE1
• Official Name: endothelin converting enzyme 1
• Aliases and Previous Symbols: N/A
• Entrez ID: 1889
• UniProt: P42892
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Sep 2009].
• UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 6098
• Expression level (log2 read counts): 5.64

Expression Distribution

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ECE1 Expression in NALM6 Cells: 5.64