EEA1

Entrez Summary: N/A
UniProt Summary: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

serine-pyruvate aminotransferase complex
axonal spine
synaptic vesicle to endosome fusion
synaptic vesicle endosomal processing
viral RNA genome replication
1-phosphatidylinositol binding
early endosome to late endosome transport
GTP-dependent protein binding
vesicle-mediated transport between endosomal compartments
viral genome replication
extrinsic component of plasma membrane
vesicle fusion
organelle membrane fusion
organelle fusion
recycling endosome
membrane fusion
cytosolic transport
early endosome membrane
nucleic acid binding
viral life cycle
calmodulin binding
endosomal transport
early endosome
vesicle organization
endocytosis
import into cell
viral process
symbiotic process
interspecies interaction between organisms
zinc ion binding
membrane organization
protein homodimerization activity
intracellular transport
establishment of localization in cell
vesicle-mediated transport
membrane