EFCAB6

Gene Information
  • Official Symbol: EFCAB6
  • Official Name: EF-hand calcium binding domain 6
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 64800
  • UniProt: Q5THR3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 2709
  • Expression level (log2 read counts): 2.02

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1