ENPEP

Entrez Summary: N/A
UniProt Summary: Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of angiotensin levels in blood
angiotensin maturation
regulation of systemic arterial blood pressure by circulatory renin-angiotensin
metalloaminopeptidase activity
regulation of systemic arterial blood pressure by renin-angiotensin
aminopeptidase activity
peptide catabolic process
peptide hormone processing
regulation of systemic arterial blood pressure by hormone
regulation of systemic arterial blood pressure mediated by a chemical signal
endocrine process
brush border
glomerulus development
peptide binding
apical part of cell
regulation of systemic arterial blood pressure
nephron development
protein processing
regulation of blood pressure
hormone metabolic process
protein maturation
cytoplasmic vesicle
kidney development
renal system development
lysosomal membrane
angiogenesis
apical plasma membrane
urogenital system development
blood circulation
external side of plasma membrane
circulatory system process
blood vessel morphogenesis
blood vessel development
vasculature development
cardiovascular system development
peptide metabolic process
regulation of hormone levels
cell population proliferation
tube morphogenesis
cellular amide metabolic process