FAM101B

Entrez Summary: N/A
UniProt Summary: Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in the formation of cartilaginous skeletal elements. {ECO:0000250|UniProtKB:Q5SVD0}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Expression Distribution

negative regulation of chondrocyte development
regulation of chondrocyte development
negative regulation of bone mineralization involved in bone maturation
regulation of bone mineralization involved in bone maturation
actin filament bundle
negative regulation of bone development
filamin binding
negative regulation of bone mineralization
negative regulation of chondrocyte differentiation
regulation of bone development
negative regulation of biomineral tissue development
negative regulation of biomineralization
negative regulation of cartilage development
regulation of chondrocyte differentiation
actin filament bundle organization
epithelial to mesenchymal transition
regulation of cartilage development
negative regulation of ossification
regulation of bone mineralization
regulation of biomineral tissue development
regulation of biomineralization
mesenchymal cell differentiation
regulation of ossification
mesenchyme development
skeletal system morphogenesis
actin filament organization
negative regulation of cell development
supramolecular fiber organization
actin cytoskeleton organization
skeletal system development
actin filament-based process
negative regulation of cell differentiation
regulation of cell development
negative regulation of developmental process
animal organ morphogenesis
cytoskeleton organization
negative regulation of multicellular organismal process
tissue development
regulation of cell differentiation