FAM154A

Entrez Summary: N/A
UniProt Summary: May play a role in the regulation of cilium length. Stabilizes microtubules at low temperature. {ECO:0000269|PubMed:25673876}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

cold acclimation
axonemal microtubule
cellular response to cold
positive regulation of cilium assembly
microtubule anchoring
sperm flagellum
response to cold
positive regulation of organelle assembly
regulation of cilium assembly
positive regulation of plasma membrane bounded cell projection assembly
motile cilium
ciliary basal body
centriole
response to temperature stimulus
protein stabilization
regulation of plasma membrane bounded cell projection assembly
regulation of cell projection assembly
regulation of organelle assembly
microtubule binding
regulation of protein stability
cytoskeleton
positive regulation of cell projection organization
microtubule cytoskeleton organization
positive regulation of cellular component biogenesis
positive regulation of organelle organization
microtubule-based process
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
regulation of cellular component biogenesis
cytoskeleton organization
cell projection organization
response to abiotic stimulus
positive regulation of cellular component organization
regulation of organelle organization
cellular response to stress