FAM210B

Entrez Summary: N/A
UniProt Summary: Plays a role in erythroid differentiation (PubMed:26968549). Involved in cell proliferation and tumor cell growth suppression (PubMed:28594398). Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner (PubMed:28594398). {ECO:0000269|PubMed:26968549, ECO:0000269|PubMed:28594398}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

intrinsic component of membrane
erythrocyte maturation
positive regulation of erythrocyte differentiation
erythrocyte development
cellular response to estradiol stimulus
regulation of erythrocyte differentiation
myeloid cell development
erythrocyte differentiation
erythrocyte homeostasis
positive regulation of myeloid cell differentiation
myeloid cell homeostasis
anatomical structure maturation
response to estradiol
cell maturation
mitochondrial outer membrane
positive regulation of hemopoiesis
homeostasis of number of cells
myeloid cell differentiation
regulation of myeloid cell differentiation
developmental maturation
regulation of hemopoiesis
cellular response to lipid
cellular response to organic cyclic compound
hemopoiesis
cellular response to hormone stimulus
hematopoietic or lymphoid organ development
immune system development
response to lipid
response to hormone
response to organic cyclic compound
positive regulation of cell differentiation
cellular response to oxygen-containing compound
positive regulation of immune system process
cellular response to endogenous stimulus
positive regulation of developmental process
response to endogenous stimulus
response to oxygen-containing compound
homeostatic process
cell development
regulation of immune system process