FAM3C

Entrez Summary: N/A
UniProt Summary: May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

platelet dense granule lumen
negative regulation of gluconeogenesis
negative regulation of cellular carbohydrate metabolic process
regulation of gluconeogenesis
negative regulation of carbohydrate metabolic process
negative regulation of small molecule metabolic process
regulation of carbohydrate biosynthetic process
regulation of glucose metabolic process
platelet degranulation
regulation of cellular carbohydrate metabolic process
cytokine activity
regulation of carbohydrate metabolic process
regulation of small molecule metabolic process
regulated exocytosis
exocytosis
Golgi apparatus
secretion by cell
export from cell
secretion
negative regulation of cellular biosynthetic process
negative regulation of biosynthetic process
extracellular region
vesicle-mediated transport