FBP2

Entrez Summary: N/A
UniProt Summary: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. {ECO:0000269|PubMed:17350621, ECO:0000269|PubMed:18214967}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

fructose 1,6-bisphosphate 1-phosphatase activity
sucrose biosynthetic process
sucrose metabolic process
disaccharide biosynthetic process
fructose 1,6-bisphosphate metabolic process
fructose 6-phosphate metabolic process
disaccharide metabolic process
fructose metabolic process
oligosaccharide biosynthetic process
gluconeogenesis
hexose biosynthetic process
oligosaccharide metabolic process
monosaccharide biosynthetic process
cellular carbohydrate biosynthetic process
glucose metabolic process
carbohydrate biosynthetic process
Z disc
hexose metabolic process
cellular carbohydrate metabolic process
monosaccharide metabolic process
dephosphorylation
carbohydrate metabolic process
cell junction
small molecule biosynthetic process
organophosphate metabolic process
carbohydrate derivative metabolic process
identical protein binding
small molecule metabolic process