FBXO42

Gene Information
  • Official Symbol: FBXO42
  • Official Name: F-box protein 42
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 54455
  • UniProt: Q6P3S6
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation. {ECO:0000269|PubMed:19509332}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 3429
  • Expression level (log2 read counts): 5.24

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1