FCHSD2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

stereocilium shaft
positive regulation of Arp2/3 complex-mediated actin nucleation
multi-organism membrane organization
positive regulation of actin nucleation
regulation of Arp2/3 complex-mediated actin nucleation
multi-organism cellular process
clathrin-dependent endocytosis
regulation of actin nucleation
phosphatidylinositol-3,4-bisphosphate binding
neuromuscular synaptic transmission
phosphatidylinositol-3,4,5-trisphosphate binding
clathrin-coated pit
neuromuscular junction
positive regulation of actin filament polymerization
recycling endosome
positive regulation of protein polymerization
regulation of actin filament polymerization
regulation of actin polymerization or depolymerization
regulation of actin filament length
positive regulation of supramolecular fiber organization
positive regulation of cytoskeleton organization
regulation of protein polymerization
receptor-mediated endocytosis
positive regulation of protein complex assembly
regulation of actin filament organization
regulation of actin cytoskeleton organization
regulation of supramolecular fiber organization
regulation of cellular component size
regulation of actin filament-based process
anterograde trans-synaptic signaling
chemical synaptic transmission
trans-synaptic signaling
regulation of protein complex assembly
synaptic signaling
regulation of anatomical structure size
positive regulation of cellular component biogenesis
regulation of cytoskeleton organization
cell junction
endocytosis
positive regulation of organelle organization